BDBM289014 US10093650, Example 15::US10329273, Example 15::US11479538, Example 15

SMILES CC(C)Cn1ccc(n1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1F)C(F)(F)F)n1nn[nH]c1=O

InChI Key InChIKey=GSPNLIJIYRHJOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289014   

LigandPNGBDBM289014(US10093650, Example 15 | US10329273, Example 15 | ...)
Affinity DataIC50: 145nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM289014(US10093650, Example 15 | US10329273, Example 15 | ...)
Affinity DataIC50: 145nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM289014(US10093650, Example 15 | US10329273, Example 15 | ...)
Affinity DataIC50: 145nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent