BDBM28898 2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid::rhodanine derivative, 57

SMILES OC(=O)CN1C(=S)S\C(=C/c2csc3ccccc23)C1=O

InChI Key InChIKey=OUWYJOICAYBELE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 28898   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: 1.30E+4nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: 2.00E+5nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details Article
PubMed