BDBM288684 (E)-3-(4-((6R,8R/6S,8S)-7-isobutyl-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)phenyl)acrylic acid::US10087191, Example 102

SMILES CC(C)CN1C(C)Cc2c(ccc3[nH]ncc23)C1c1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=CZDSGCCSLPSVEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288684   

TargetG-protein coupled estrogen receptor 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM288684((E)-3-(4-((6R,8R/6S,8S)-7-isobutyl-8-methyl-6,7,8,...)
Affinity DataIC50: 0.640nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair
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Date in BDB:
1/18/2019
Entry Details
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