BDBM288660 (E)-3-(4-((1R,3R/1S,3S)-6-(1-ethyl-1H-pyrazol-4-yl)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridin-1-yl)-3,5-difluorophenyl)acrylic acid::US10087191, Example 76

SMILES CCn1cc(cn1)-c1ccc2oc3C(N(CC(C)(C)F)C(C)Cc3c2c1)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=YSVIKKDLEGRPHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288660   

TargetG-protein coupled estrogen receptor 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM288660((E)-3-(4-((1R,3R/1S,3S)-6-(1-ethyl-1H-pyrazol-4-yl...)
Affinity DataIC50: 1.39nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
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