BDBM288257 7-Chloro-5-(2-cyclopropyl-8-methyl-6-(trifluoromethyl)-::US10087185, Example 75

SMILES Cc1cc(c(-c2cc3CC(=O)Nc3c(Cl)c2)n2nc(nc12)C1CC1)C(F)(F)F

InChI Key InChIKey=VCRYMMDEEDWYRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288257   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288257(US10087185, Example 75 | 7-Chloro-5-(2-cyclopropyl...)
Affinity DataIC50: 0.126nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2019
Entry Details
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