BDBM288244 2-Cyclopropyl-6-(4-fluorophenyl)-5-(7-methyl-1H-indazol-5-yl)-::US10087185, Example 62

SMILES Cc1cc(cc2cn[nH]c12)-c1c(ccc2nc(nn12)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=DPJHLFHYHCWZLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288244   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288244(US10087185, Example 62 | 2-Cyclopropyl-6-(4-fluoro...)
Affinity DataIC50: 0.126nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2019
Entry Details
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