BDBM287955 N-(4-(4-((2-(4-methylpiperazin-1-yl)-2- phenylethyl)amino)quinazolin-2- yl)phenyl)methanesulfonamide::US10087148, Example 23

SMILES CN1CCN(CC1)C(CNc1nc(nc2ccccc12)-c1ccc(NS(C)(=O)=O)cc1)c1ccccc1

InChI Key InChIKey=VHRIHFKRNILXQE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287955   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287955(N-(4-(4-((2-(4-methylpiperazin-1-yl)-2- phenylethy...)
Affinity DataEC50:  62nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
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