BDBM287946 2-(4-(dimethylamino)phenyl)-N-(2- phenyl-2-(1H-pyrrol-2- yl)ethyl)quinazolin-4-amine::US10087148, Example 14

SMILES CN(C)c1ccc(cc1)-c1nc(NCC(c2ccc[nH]2)c2ccccc2)c2ccccc2n1

InChI Key InChIKey=XLHLJNDKMOMHJF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287946   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287946(2-(4-(dimethylamino)phenyl)-N-(2- phenyl-2-(1H-pyr...)
Affinity DataEC50:  5.60nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
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