BDBM287938 N-(4-(4-((2-cyclohexyl-2- phenylethyl)amino)quinazolin-2- yl)phenyl)methanesulfonamide::US10087148, Example 6

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1nc(NCC(C2CCCCC2)c2ccccc2)c2ccccc2n1

InChI Key InChIKey=ILCVJNNEXILAQD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287938   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287938(N-(4-(4-((2-cyclohexyl-2- phenylethyl)amino)quinaz...)
Affinity DataEC50:  16nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
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