BDBM287583 US9567324, 23

SMILES Nc1ncc(cc1C#Cc1cccc(c1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)C(=O)N=S1(=O)CCOCC1

InChI Key InChIKey=NAZMMUDKWQHGKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 287583   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM287583(US9567324, 23)
Affinity DataIC50: 39nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM287583(US9567324, 23)
Affinity DataIC50: 13nMpH: 7.4Assay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
Go to US Patent