BDBM287088 N-(1-[2-(Piperidin-1- yl)ethyl]-1H-pyrazolo[3,4- d]pyrimidin-4-yl)-1- adamantylcarboxamide maleate::US9567338, 4

SMILES O=C(Nc1ncnc2n(CCN3CCCCC3)ncc12)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287088   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandPNGBDBM287088(N-(1-[2-(Piperidin-1- yl)ethyl]-1H-pyrazolo[3,4- d...)
Affinity DataKi:  12.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent