BDBM286228 3-cyclopropyl-6-fluoro-2-(6- methylpyridin-3-yl)imidazo[1,2- a]pyridine::US9518055, Example 30

SMILES Cc1ccncc1-c1nc2ccc(F)cn2c1C1CC1

InChI Key InChIKey=AOWOOZVSVDTJLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286228   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286228(US9518055, Example 30 | 3-cyclopropyl-6-fluoro-2-(...)
Affinity DataIC50: 3.20nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286228(US9518055, Example 30 | 3-cyclopropyl-6-fluoro-2-(...)
Affinity DataIC50: 1.07E+3nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent