BDBM286222 6-fluoro-3-methyl-2-(5- methylpyridin-3-yl)imidazo[1,2- a]pyridine::US9518055, Example 19

SMILES Cc1c(nc2ccc(F)cn12)-c1cncc(C)c1

InChI Key InChIKey=SRZDNWBHPIJBNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286222   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286222(US9518055, Example 19 | 6-fluoro-3-methyl-2-(5- me...)
Affinity DataIC50: 0.450nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286222(US9518055, Example 19 | 6-fluoro-3-methyl-2-(5- me...)
Affinity DataIC50: 40.7nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent