BDBM286061 (S)-N-(2-(4-Chlorophenyl)-1-(-tetrahydrofuran-3-yl)-1H-indol-5-yl)-2-(difluoromethyl)-5-(((2-fluoro-2-methyl-propanoyl)amino)methyl)nicotinamide::US10081629, Example 46

SMILES CC(C)(F)C(=O)NCc1cnc(C(F)F)c(c1)C(=O)Nc1cnc2n(ccc2c1)[C@H]1CCOC1

InChI Key InChIKey=BIVMYVPPZIELQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286061   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286061(US10081629, Example 46 | (S)-N-(2-(4-Chlorophenyl)...)
Affinity DataIC50: 2.71nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286061(US10081629, Example 46 | (S)-N-(2-(4-Chlorophenyl)...)
Affinity DataIC50: 24.7nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent