BDBM286033 2-Chloro-N-(2-(4-chlorophenyl)indazol-5-yl)-5-((2,2-dimethylpropanoylamino)methyl)benzamide::US10081629, Example 16

SMILES CC(C)(C)C(=O)NCc1ccc(Cl)c(c1)C(=O)Nc1ccc2nn(cc2c1)-c1ccc(Cl)cc1

InChI Key InChIKey=CENPKMYVZBCQQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286033   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286033(US10081629, Example 16 | 2-Chloro-N-(2-(4-chloroph...)
Affinity DataIC50: 9.31nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286033(US10081629, Example 16 | 2-Chloro-N-(2-(4-chloroph...)
Affinity DataIC50: 26.2nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent