BDBM286027 2-(Difluoromethyl)-N-(1-methyl-2-(4-(trifluoromethyl)phenyl)-1Hindol-5-yl)5-((2-methylpropanoylamino)methyl)-nicotinamide::US10081629, Example 9

SMILES CC(C)C(=O)NCc1cnc(C(F)F)c(c1)C(=O)Nc1ccc2n(C)c(cc2c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WEVFXPNBGNHCLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286027   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286027(US10081629, Example 9 | 2-(Difluoromethyl)-N-(1-me...)
Affinity DataIC50: 15.6nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286027(US10081629, Example 9 | 2-(Difluoromethyl)-N-(1-me...)
Affinity DataIC50: 11.8nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent