BDBM285998 (+/-)-Methyl N-[8-({2-[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]ethyl}carbamoyl)-4-methyl-2,10-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-1,9-benzodiazacyclododecin-13-yl]carbamate::US10081623, Example 11

SMILES COC(=O)Nc1ccc2c(NC(=O)CC(C)CCCC(NC2=O)C(=O)NCCc2cc(Cl)ccc2-n2cnnn2)c1

InChI Key InChIKey=INAKQOFTONZECB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285998   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM285998(US10081623, Example 11 | (+/-)-Methyl N-[8-({2-[5...)
Affinity DataKi:  73.6nMpH: 7.4Assay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
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