BDBM285854 US10081617, Example 2::methyl [4-(2-{3-[5-chloro- 2-(1H-tetrazol-1- yl)phenyl]-1-oxido-6,7- dihydro-5H- cyclopenta[b]pyridin-7- yl}-4-methyl-1H-imidazol- 5-yl)phenyl]carbamate

SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1C)C1CCc2cc(c[n+]([O-])c12)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=LDCYIIFQALTBKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285854   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM285854(US10081617, Example 2 | methyl [4-(2-{3-[5-chloro-...)
Affinity DataIC50: 0.780nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
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