BDBM285649 1,5-dimethyl-6-{4-[(3-methyl[1,2]oxazolo[4,5-c]pyridin-4-yl)oxy]phenyl}pyrimidine-2,4(1H,3H)-dione::US10077272, Example 15::US9868744, 15

SMILES Cc1noc2ccnc(Oc3ccc(cc3)-c3c(C)c(=O)[nH]c(=O)n3C)c12

InChI Key InChIKey=CANYWAHWNTVTOT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285649   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285649(US10077272, Example 15 | 1,5-dimethyl-6-{4-[(3-met...)
Affinity DataKi:  280nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285649(US10077272, Example 15 | 1,5-dimethyl-6-{4-[(3-met...)
Affinity DataKi:  280nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent