BDBM285646 5-[4-(1H-imidazo[4,5-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyrimidine-4-carbonitrile::US10077272, Example 12::US9868744, 12

SMILES Cc1cc(Oc2nccc3[nH]cnc23)ccc1-c1c(C)ncnc1C#N

InChI Key InChIKey=UMAZSPWKQMTIHK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285646   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285646(US10077272, Example 12 | 5-[4-(1H-imidazo[4,5-c]py...)
Affinity DataKi:  367nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285646(US10077272, Example 12 | 5-[4-(1H-imidazo[4,5-c]py...)
Affinity DataKi:  367nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent