BDBM285635 4-[4-(4,6-Dimethylpyrimidin-5-yl)-3-methylphenoxy]furo[2,3-d]pyrimidine (1)::US10077272, Example 1::US9868744, 1

SMILES Cc1cc(Oc2ncnc3occc23)ccc1-c1c(C)ncnc1C

InChI Key InChIKey=BAFMQXISSSJWTB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285635   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285635(US10077272, Example 1 | 4-[4-(4,6-Dimethylpyrimidi...)
Affinity DataKi:  166nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285635(US10077272, Example 1 | 4-[4-(4,6-Dimethylpyrimidi...)
Affinity DataKi:  166nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent