BDBM285593 US10077269, Example 66::US10669279, Example 66::US9598421, Example 66::azetidin-1-yl[3-(3-chloro-2,4-dimethylphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone,formate salt

SMILES Cc1ccc(-c2c(nc3cccnn23)C(=O)N2CCC2)c(C)c1Cl

InChI Key InChIKey=FQEXMVRMBJXJHA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 285593   

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 41nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 41nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 3.39E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 3.39E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285593(US10077269, Example 66 | azetidin-1-yl[3-(3-chloro...)
Affinity DataIC50: 3.39E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent