BDBM285550 4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazin-3-yl]-2-fluorobenzonitrile::US10077269, Example 23::US10669279, Example 23::US9598421, Example 23

SMILES Fc1cc(ccc1C#N)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=COQGBMKNVJUVAB-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285550   

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 15.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 15.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 15.1nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 30.5nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 30.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 30.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 45.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 45.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 45.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 4.13E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 4.13E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285550(US10077269, Example 23 | 4-[2-(azetidin-1-ylcarbon...)
Affinity DataIC50: 4.13E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent