BDBM284932 US10023583, Example 5

SMILES COC(=O)[C@@](O)(Cc1nccc2oc(CCC3CC3)cc12)[C@@H](N)CSC

InChI Key InChIKey=GTBZNNHYIZEBEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 284932   

TargetLeucyl-cystinyl aminopeptidase(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM284932(US10023583, Example 5)
Affinity DataIC50: 59nMAssay Description:Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
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TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandPNGBDBM284932(US10023583, Example 5)
Affinity DataIC50: 89nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent