BDBM28487 (2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(13),2,4,6,9,11-hexaene-4-sulfonamido}butanoic acid::dibenzofuran (DBF) scaffold, (S)-2b

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2oc3ccccc3c2c1)C(O)=O

InChI Key InChIKey=YGNCGRVNRKDKCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 28487   

TargetMacrophage metalloelastase(Human)
Wyeth Research

LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 600nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed