BDBM28427 (2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane-3,4-diol::AdoMet substrate analogue, 14c

SMILES CN(CCCCON)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c2ncnc(N)c2[nH]c1=O

InChI Key InChIKey=ZOLZMJNERKHVOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28427   

TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28427((2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-...)
Affinity DataIC50: 11nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed