BDBM28406 (2E)-3-{3-[6-(4-acetyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid::pyrazine inhibitor, 9

SMILES CC(=O)N1CCCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1

InChI Key InChIKey=SSWBAEBPHNUZNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28406   

TargetSerine/threonine-protein kinase pim-2(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM28406((2E)-3-{3-[6-(4-acetyl-1,4-diazepan-1-yl)pyrazin-2...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed