BDBM28353 1-(4-methylphenyl)-5-oxo-N-[2-(phenylsulfanyl)phenyl]pyrrolidine-3-carboxamide::ZINC1064012, 22

SMILES Cc1ccc(cc1)N1CC(CC1=O)C(=O)Nc1ccccc1Sc1ccccc1

InChI Key InChIKey=MOQRRTTUQUZKAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28353   

TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28353(1-(4-methylphenyl)-5-oxo-N-[2-(phenylsulfanyl)phen...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28353(1-(4-methylphenyl)-5-oxo-N-[2-(phenylsulfanyl)phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2009
Entry Details Article
PubMed