BDBM28341 (9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxopropyl]-decahydropyrido[1,2-a]piperazine-5,2-diium::ZINC04427277, 1

SMILES [H][C@]12CCCC[NH+]1CC[NH+](CCC(=O)N1c3ccccc3Sc3ccc(Cl)cc13)C2

InChI Key InChIKey=UDGRQZRWGPZOAJ-UHFFFAOYSA-P

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28341   

TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50: 3.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50: 3.19E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2009
Entry Details Article
PubMed