BDBM282853 6-(1-(bicyclo[1.1.1]pentan-1-yl)-4-(3-chloro-4- fluorophenyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazine-3-carbonitrile::US10287295, Example 59'::US11352360, Example 59'::US9884868, Example 59'
SMILES Fc1ccc(cc1Cl)-c1ncn(c1-c1ccc2ncc(C#N)n2n1)C12CC(C1)C2
InChI Key InChIKey=IUJYDCJZGPLXMG-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 282853
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 7.55E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair