BDBM282586 US9884828, 2-43

SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccc(F)cc1)C(N)=O

InChI Key InChIKey=JQNIXUJZAIWKNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282586   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM282586(US9884828, 2-43)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
Go to US Patent