BDBM281496 N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-6-yl]- 2-methylpyridin-3- yl}-N,N- dimethylsulfamide::US10022387, Example 22::US10596184, Example 22::US9586949, Example 22

SMILES CN(C)S(=O)(=O)Nc1cc(cnc1C)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=YODVCGCZVKUHMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 281496   

LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMpH: 6.7 T: 2°CAssay Description:γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
Go to US Patent

LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
Go to US Patent

LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMAssay Description:PI3K-gamma:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

LigandPNGBDBM281496(US9586949, Example 22 | US10022387, Example 22 | N...)
Affinity DataIC50: 250nMAssay Description:PI3Kdelta: The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent