BDBM2814 Alkenyldiarylmethane (ADAM) 11b::Alkenyldiarylmethanes (ADAM) 11b::Methyl (5E)-6-[4-methoxy-5-(methoxycarbonyl)-3-methylphenyl]hex-5-enoate::methyl 2-methoxy-5-[(1E)-6-methoxy-6-oxohex-1-en-1-yl]-3-methylbenzoate

SMILES COC(=O)CCC\C=C\c1cc(C)c(OC)c(c1)C(=O)OC

InChI Key InChIKey=HJBAPWFYBUZXKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2814   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2814(methyl 2-methoxy-5-[(1E)-6-methoxy-6-oxohex-1-en-1...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed