BDBM28121 3-cyanoquinoline, 6::4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfanyl]phenyl}amino)-7-{[3-(dimethylamino)propyl](methyl)amino}-6-methoxyquinoline-3-carbonitrile

SMILES COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(cnc2cc1N(C)CCCN(C)C)C#N

InChI Key InChIKey=HNQAZVSIDPRVTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28121   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28121(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 150nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed