BDBM2808 Alkenyldiarylmethane (ADAM) 5b::Alkenyldiarylmethanes (ADAM) 5b::methyl 3-chloro-2-methoxy-5-[(1Z)-6-methoxy-1-[4-methoxy-3-(methoxycarbonyl)phenyl]-6-oxohex-1-en-1-yl]benzoate

SMILES COC(=O)CCC\C=C(\c1ccc(OC)c(c1)C(=O)OC)c1cc(Cl)c(OC)c(c1)C(=O)OC

InChI Key InChIKey=VLFBJAMHQKHBAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2808   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2808(Alkenyldiarylmethane (ADAM) 5b | methyl 3-chloro-2...)
Affinity DataIC50: 587nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed