BDBM280449 US10030012, Example 79::ethyl 4-{[3-(3,5- dimethyl-1H- pyrazol-1-yl) pyrrolidin-1-yl] methyl}piperidine- 1-carboxylate

SMILES CCOC(=O)N1CCC(CN2CCC(C2)n2nc(C)cc2C)CC1

InChI Key InChIKey=ALSIMRULFADWHS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280449   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280449(ethyl 4-{[3-(3,5- dimethyl-1H- pyrazol-1-yl) pyrro...)
Affinity DataEC50:  340nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
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