BDBM280443 US10030012, Example 73::ethyl 4-{4-[2- (1-methyl-1H- pyrazol- 4-yl)pyridin-3- yl]piperidin-1- yl}azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1-c1cnn(C)c1

InChI Key InChIKey=ZSQMTLNYPRVOGJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280443   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280443(ethyl 4-{4-[2- (1-methyl-1H- pyrazol- 4-yl)pyridin...)
Affinity DataEC50:  650nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent