BDBM280439 US10030012, Example 69::ethyl 4-{4-[5- (trifluoromethyl)- 1H-pyrazol-1- yl]piperidin-1- yl}azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1C(F)(F)F

InChI Key InChIKey=DEZNYIIERUVVBD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280439   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280439(ethyl 4-{4-[5- (trifluoromethyl)- 1H-pyrazol-1- yl...)
Affinity DataEC50:  630nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
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TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280439(ethyl 4-{4-[5- (trifluoromethyl)- 1H-pyrazol-1- yl...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent