BDBM280437 US10030012, Example 67::ethyl 4-(4-{2- [(cyclopropyl- methyl)amino] pyridin-3- yl}piperidin-1- yl)azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1NCC1CC1

InChI Key InChIKey=GLPSQHHYZQUCGU-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280437   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280437(ethyl 4-(4-{2- [(cyclopropyl- methyl)amino] pyridi...)
Affinity DataEC50:  990nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent