BDBM280425 US10030012, Example 55::ethyl 4-{4-[2- (propan-2- yloxy)pyridin-3- yl]piperidin-1- yl}azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1OC(C)C

InChI Key InChIKey=GMWKZZZIYCJKLL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280425   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280425(ethyl 4-{4-[2- (propan-2- yloxy)pyridin-3- yl]pipe...)
Affinity DataEC50:  130nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280425(ethyl 4-{4-[2- (propan-2- yloxy)pyridin-3- yl]pipe...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent