BDBM280307 US10029993, Example 159a

SMILES CN1CCO[C@@H](CNC(=O)CN2CCN(CC2)c2nncc(n2)-c2ccc(F)cc2)C1

InChI Key InChIKey=OYDIQTRGUXASTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280307   

TargetCytochrome P450 11B2, mitochondrial(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM280307(US10029993, Example 159a)
Affinity DataIC50: 7.70nMpH: 7.4 T: 2°CAssay Description:The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent