BDBM279801 PMPG prodrug, R form::US10035814, Compound 142715

SMILES CC(C)OC(=O)OCOP(=O)(COC(C)Cn1cnc2c1nc(N)[nH]c2=O)OCOC(=O)OC(C)C

InChI Key InChIKey=XMEFOQQJHRHEMQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279801   

TargetTelomerase protein component 1(Human)
Geron

US Patent
LigandPNGBDBM279801(US10035814, Compound 142715 | PMPG prodrug, R form)
Affinity DataEC50:  2.15E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent