BDBM27977 6-Ethynylthieno[2,3-d]pyrimidine, 12::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{2-[(2R)-pyrrolidin-2-yl]ethynyl}thieno[2,3-d]pyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)C#C[C@H]3CCCN3)cc2Cl)c1

InChI Key InChIKey=TWIUFSQIKGYUBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27977   

LigandPNGBDBM27977(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{...)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27977(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{...)
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27977(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{...)
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed