BDBM27971 6-Ethynylthieno[3,2-d]pyrimidine, 6::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-ethynylthieno[3,2-d]pyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C)cc2Cl)c1

InChI Key InChIKey=RBBZLSVNHVBMRU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27971   

LigandPNGBDBM27971(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-e...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27971(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-e...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27971(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-e...)
Affinity DataIC50: 66nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP/[gamma-33P]ATP, and purified kinase in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed