BDBM27955 (-)-Zilpaterol::(9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diazatricyclo[6.4.1.0^{4,13}]trideca-4(13),5,7-trien-2-one

SMILES CC(C)N[C@@H]1CCn2c3c(cccc3[nH]c2=O)[C@H]1O

InChI Key InChIKey=ZSTCZWJCLIRCOJ-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27955   

TargetBeta-2 adrenergic receptor(Human)
Intervet Innovation

LigandPNGBDBM27955((9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  320nM ΔG°:  -8.77kcal/mole IC50: 620nM EC50:  8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Intervet Innovation

LigandPNGBDBM27955((9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  1.30E+5nM ΔG°:  -5.24kcal/mole IC50: 3.20E+5nM EC50: >1.00E+6nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed