BDBM279459 Example 57 1-(1-(3,4-dichlorophenyl)cyclobutyl)-N-(2-(ethylthio)ethyl)propan-1-amine::US10035761, Compound 13f

SMILES CCSCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=VVMJMYKYAKFHJP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 279459   

TargetSodium-dependent dopamine transporter(Human)
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM279459(US10035761, Compound 13f | Example 57 1-(1-(3,4-di...)
Affinity DataKi:  49.2nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM279459(US10035761, Compound 13f | Example 57 1-(1-(3,4-di...)
Affinity DataKi:  119nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Revivia Pharmaceuticals

US Patent
LigandPNGBDBM279459(US10035761, Compound 13f | Example 57 1-(1-(3,4-di...)
Affinity DataKi:  224nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent