BDBM279193 4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chloro-2-furyl)methyl]-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide::US10034864, Example 21::US10967060, Example 21::US11207302, Example 21::US20240173303, Example 21::US9789094, 21

SMILES NS(=O)(=O)NCCNc1nonc1C(NCc1cc(Cl)co1)=NO

InChI Key InChIKey=RDUXAXXIUDRDCQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 279193   

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
The University of Chicago

US Patent
LigandPNGBDBM279193(4-({2-[(Aminosulfonyl)amino]ethyl}amino)-N-[(4-chl...)
Affinity DataIC50: 750nMAssay Description:Human indoleamine 2,3-dioxygenase (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent