BDBM278967 5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxyethyl]-3-methyl-tetrahydrofuran-2-yl]-6H-thiazolo[4,5-d]pyrimidine-2,7-dione::US10040815, Example 31::US10618929, Example 31

SMILES C[C@H](O)[C@@H]1C[C@@H](C)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O

InChI Key InChIKey=UOFOFCRGWCROKD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 278967   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM278967(5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxyethyl]-3-me...)
Affinity DataEC50:  7.00E+4nMAssay Description:A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat.#: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM278967(5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxyethyl]-3-me...)
Affinity DataEC50:  7.00E+4nMAssay Description:A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat. #: hkb-ht1r7, San Diego, Calif., USA). These cells were designed for studyin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent