BDBM27843 2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piperazin-1-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-N-methylbenzamide::4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 29

SMILES CNC(=O)c1c(F)cccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(CC2)C(C)C)nc2[nH]ccc12

InChI Key InChIKey=ULDVOXNXKFGVKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27843   

LigandPNGBDBM27843(2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2009
Entry Details Article
PubMed