BDBM2781 Alkenyldiarylmethane (ADAM) 23a::Alkenyldiarylmethanes (ADAM) 23a::Propyl 3,3-Dimethyl-4,4-dimethoxy-5,5-bis(methoxycarbonyl)-6,6-diphenyl-5-hexenoate::methyl 2-methoxy-5-{1-[4-methoxy-3-(methoxycarbonyl)-5-methylphenyl]-6-oxo-6-propoxyhex-1-en-1-yl}-3-methylbenzoate

SMILES [#6]-[#6]-[#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]\[#6]=[#6](/c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6])-c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]

InChI Key InChIKey=FAWLEAORIOOKJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2781   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2781(Alkenyldiarylmethane (ADAM) 23a | methyl 2-methoxy...)
Affinity DataIC50: 2.97E+4nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed